What is ‘Covid rebound’ and how is it connected to Big Pharma?

Rebound
At the Global Health Forum
Covid resurgence
What is Covid rebound?
Reducing risk by 87%
Symptoms
Blockbuster drug
Developing resistance
The exception
Working as usual
Extended treatment
Fauci's case
A second run of Paxlovid
Big pharma
Market vs. public
More questions than answers
Rebound

Dr. Anthony Fauci, the Biden Administration’s chief medical advisor, announced he suffered a ‘rebound’ on his Covid-19 infection after taking Paxlovid, an antiviral pill by Pfizer. However, he’s hardly the only one.

At the Global Health Forum

“I turned positive about two weeks ago, with very minimal symptoms. When they increased, given my age, I went on Paxlovid for five days”, Fauci said on during July 28, during the Foreign Policy’s Global Health Forum and as quoted by CNN.

Covid resurgence

After five days on the drug, CNN reports, Fauci tested negative. He had three consecutive days of negative tests. However, after the fourth day, he tested positive again.

Image: Medakit Ltd / Unsplash

What is Covid rebound?

‘Covid rebound’ is defined by CBS news as “a reemergence of Covid symptoms” after patients take the Pfizer pill.

Reducing risk by 87%

Reuters explains that high-risk patients on Paxlovid have 87% less chance of hospitalization or death if taken within the first five days of showing Covid-19 symptoms.

Symptoms

However, Covid-19 levels and symptoms are shown to have reappeared after completing the treatment, raising questions about how effective Paxlovid really is.

Blockbuster drug

The publication Science comments that prescriptions of Paxlovid have skyrocketed in the United States through July.

Developing resistance

Nonetheless, scientists are concerned that Paxlovid’s popularity might be its ruin. New studies, Science points out, suggest that Covid-19 can mutate and develop more resistance against the antiviral drug.

The exception

CNN reports that, to date, cases involving Covid-19 rebound have been limited to small studies and anecdotal evidence.

Working as usual

According to Reuters, when researchers isolated a sample of the Omicron variant from a rebound patient, they found that it was still sensitive to Paxlovid.

Extended treatment

The researchers concluded that those going through Covid rebound might require extended treatment.

Fauci's case

This was Anthony Fauci’s case. After the first course of Paxlovid, the head of the National Institute of Allergy and Infectious Diseases has told that his symptoms got worse after having tested negative.

A second run of Paxlovid

Fauci’s doctor prescribed him a second run on Paxlovid, which seems to have helped him to get through the disease.

Big pharma

Science writes that other pharmaceutical companies are racing to complete clinical trials of their own Covid-19 treatment.

Market vs. public

Pfizer has been criticized for not allowing Paxlovid to be easily available for trials of combination therapies. As it dominates the market, there are fears that sooner or later it may become a matter of public health.

More questions than answers

David Ho, a virologist at Columbia University, commented to Science that when you corner a virus, it always finds a way to escape. This raises the question that if Covid-19 is confronted from a single side, that is with a single type of vaccine, how long will it take until it learns to go around it.

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